Joseph L Witztum Selected Research

Apolipoproteins B (ApoB)

1/2020	ApoCIII-Lp(a) complexes in conjunction with Lp(a)-OxPL predict rapid progression of aortic stenosis.
1/2019	Lipoprotein(a) and Oxidized Phospholipids Promote Valve Calcification in Patients With Aortic Stenosis.
11/2018	Relationship of lipoprotein-associated apolipoprotein C-III with lipid variables and coronary artery disease risk: The EPIC-Norfolk prospective population study.
2/2017	Very-Low-Density Lipoprotein-Associated Apolipoproteins Predict Cardiovascular Events and Are Lowered by Inhibition of APOC-III.
1/2017	Oxidized Phospholipids on Apolipoprotein B-100 and Recurrent Ischemic Events Following Stroke or Transient Ischemic Attack.
1/2017	Relationship of Autoantibodies to MDA-LDL and ApoB-Immune Complexes to Sex, Ethnicity, Subclinical Atherosclerosis, and Cardiovascular Events.
1/2017	Autoantibodies and immune complexes to oxidation-specific epitopes and progression of aortic stenosis: Results from the ASTRONOMER trial.
5/2016	Effect of therapeutic interventions on oxidized phospholipids on apolipoprotein B100 and lipoprotein(a).
9/2015	Oxidized Phospholipids, Lipoprotein(a), and Progression of Calcific Aortic Valve Stenosis.
7/2015	Heritability of Biomarkers of Oxidized Lipoproteins: Twin Pair Study.

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Joseph L Witztum Research Topics

Disease

89	Atherosclerosis 01/2022 - 01/2002
29	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 02/2004
28	Inflammation (Inflammations) 01/2022 - 09/2002
16	Coronary Artery Disease (Coronary Atherosclerosis) 12/2021 - 09/2003
13	Myocardial Infarction 01/2019 - 08/2007
12	Hypertriglyceridemia 01/2022 - 04/2007
11	Aortic Valve Stenosis (Aortic Stenosis) 01/2020 - 02/2014
10	Stroke (Strokes) 03/2018 - 08/2007
9	Atherosclerotic Plaque (Atheroma) 01/2022 - 09/2002
8	Thrombosis (Thrombus) 12/2021 - 06/2005
8	Hyperlipoproteinemia Type I (Lipoprotein Lipase Deficiency, Familial) 12/2019 - 12/2014
8	Hypercholesterolemia 03/2016 - 07/2005
7	Pancreatitis 01/2021 - 12/2014
6	Hyperlipoproteinemia Type II (Familial Hypercholesterolemia) 07/2016 - 09/2003
5	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2022 - 02/2007
5	Insulin Resistance 01/2017 - 09/2003
4	Inborn Genetic Diseases (Disease, Hereditary) 01/2019 - 12/2014
4	Costello Syndrome 09/2018 - 05/2017
4	Acute Coronary Syndrome 10/2011 - 02/2003
3	Neoplasms (Cancer) 01/2021 - 01/2017
3	Injection Site Reaction 01/2021 - 11/2016
3	Osteoporosis 01/2021 - 01/2018
3	Coronary Disease (Coronary Heart Disease) 01/2019 - 04/2015
3	Transient Ischemic Attack 03/2018 - 08/2007
3	Hemorrhage 06/2017 - 07/2012
3	Obesity 04/2016 - 04/2007
3	Hyperlipidemias (Hyperlipidemia) 08/2015 - 09/2003
3	Pathologic Constriction (Stenosis) 05/2014 - 07/2005
3	Blister (Bulla) 07/2012 - 01/2002
3	Carotid Artery Diseases 10/2011 - 11/2003
3	Hypertension (High Blood Pressure) 09/2011 - 11/2003
3	Infections 10/2009 - 06/2003
2	Non-alcoholic Fatty Liver Disease 01/2021 - 03/2015
2	Death (Near-Death Experience) 01/2020 - 09/2015
2	Human Influenza (Influenza) 01/2020 - 10/2009
2	Thrombocytopenia (Thrombopenia) 01/2020 - 12/2019
2	Disease Progression 01/2020 - 01/2019
2	Necrosis 10/2019 - 11/2010
2	Aortic Valve Disease 01/2018 - 01/2017

Drug/Important Bio-Agent (IBA)

52	oxidized low density lipoproteinIBA 01/2021 - 03/2002
39	Phospholipids (Phosphatides)FDA LinkGeneric 12/2021 - 01/2002
34	LipidsIBA 01/2022 - 03/2002
32	1-penicillamyl-Leu(2)- oxytocinIBA 12/2021 - 09/2004
32	Lipoprotein(a)IBA 01/2020 - 09/2004
27	Apolipoproteins B (ApoB)IBA 01/2020 - 06/2006
26	EpitopesIBA 01/2019 - 06/2003
25	Lipoproteins (Lipoprotein)IBA 01/2022 - 01/2002
22	AntibodiesIBA 01/2021 - 06/2003
17	Apolipoprotein B-100 (Apo B 100)IBA 01/2019 - 09/2004
16	Biomarkers (Surrogate Marker)IBA 01/2022 - 09/2003
16	LDL Lipoproteins (beta Lipoproteins)IBA 01/2017 - 03/2002
15	Triglycerides (Triacylglycerol)IBA 01/2022 - 09/2003
15	CholesterolIBA 01/2018 - 06/2002
14	Malondialdehyde (Propanedial)IBA 10/2019 - 08/2004
14	Apolipoproteins E (ApoE)IBA 10/2019 - 07/2002
14	Immunoglobulin M (IgM)IBA 10/2019 - 08/2004
12	AutoantibodiesIBA 01/2017 - 12/2002
11	AntigensIBA 07/2015 - 06/2003
10	ApolipoproteinsIBA 02/2017 - 10/2004
10	LDL Receptors (LDL Receptor)IBA 03/2016 - 06/2002
9	Immunoglobulin G (IgG)IBA 01/2020 - 06/2006
8	Apolipoprotein C-IIIIBA 01/2022 - 07/2015
6	Apolipoproteins AIBA 01/2020 - 04/2005
6	Lipoprotein Lipase (Diacylglycerol Lipase)IBA 01/2019 - 12/2014
6	Proteins (Proteins, Gene)FDA Link 07/2018 - 12/2004
6	Atorvastatin (Lipitor)FDA Link 01/2017 - 09/2004
6	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2017 - 06/2006
6	Antigen-Antibody Complex (Immune Complex)IBA 01/2017 - 09/2004
6	AntioxidantsIBA 01/2015 - 09/2003
5	C-Reactive ProteinIBA 01/2022 - 09/2003
5	Messenger RNA (mRNA)IBA 01/2022 - 12/2014
5	Antisense OligonucleotidesIBA 01/2022 - 03/2015
5	Scavenger Receptors (Scavenger Receptor)IBA 01/2021 - 08/2005
5	ISIS 304801IBA 01/2021 - 12/2014
5	Biological ProductsIBA 05/2016 - 01/2002
4	LDL CholesterolIBA 01/2018 - 04/2007
4	Immunoglobulins (Immunoglobulin)IBA 03/2016 - 06/2006
4	Peptides (Polypeptides)IBA 08/2015 - 01/2011
3	Glucose (Dextrose)FDA LinkGeneric 10/2020 - 04/2016
3	Pharmaceutical PreparationsIBA 01/2020 - 10/2015
3	Single-Chain AntibodiesIBA 01/2019 - 10/2011
3	Phosphorylcholine (Phosphocholine)IBA 01/2018 - 06/2003
3	HDL LipoproteinsIBA 02/2017 - 10/2004
3	Rosuvastatin Calcium (Crestor)FDA Link 01/2017 - 06/2006
3	omega-Chloroacetophenone (Mace)IBA 01/2017 - 04/2015
3	CytokinesIBA 04/2014 - 03/2002
3	AutoantigensIBA 03/2008 - 01/2003
3	VitaminsIBA 08/2004 - 09/2003
2	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 01/2020 - 07/2010
2	AKCEA-APO(a)-LRxIBA 01/2020 - 11/2016
2	HDL CholesterolIBA 12/2019 - 02/2017
2	LigandsIBA 01/2019 - 10/2009
2	EnzymesIBA 11/2018 - 11/2010
2	Apolipoprotein C-II (ApoC2)IBA 07/2018 - 08/2015
2	Interleukin-1 (Interleukin 1)IBA 03/2018 - 05/2014
2	AcetaldehydeIBA 01/2018 - 01/2013
2	Protein Isoforms (Isoforms)IBA 01/2017 - 04/2009

Therapy/Procedure

13	Therapeutics 12/2021 - 09/2003
3	Percutaneous Coronary Intervention 07/2012 - 11/2005
2	Injections 01/2021 - 11/2016